When nucleotides connect to form DNA or RNA, the phosphate of one nucleotide attaches via a phosphodiester bond to the 3-carbon of the sugar of the next nucleotide, forming the sugar-phosphate backbone of the nucleic acid. Thymidine monophosphate is a thymine nucleotide that is part of DNA. Hence, deoxyribose is more precisely called 2-deoxyribose. The phosphate group is bonded to the 5 carbon of the sugar (see Figure 2), and when nucleotides are joined to form RNA or DNA, the phosphate of one nucleotide is joined to the sugar of the next nucleotide at its 3 carbon, to form the sugar-phosphate backbone of the nucleic acid. A. Molecules of DNA are composed of long chains of a. amino acids b. fatty acids c. monosaccharides d. nucleotides. These strong bonds form a sugar-phosphate backbone. Clear. To form a nucleotide, a base connects to the first or primary carbon of ribose or deoxyribose. I can show how this happens perfectly well by going back to a simpler diagram and not worrying about the structure of the bases. Guanine is a purine and is a nucleotide base in DNA. nucleotide A molecule formed from the bonding of a purine or a pyrimidine base with a sugar and a mono-, di- or tri-phosphate group. The remaining three DNA nucleotides have similar structure, but each has a nitrous base of its own (the top group). DNA sequencing, technique used to determine the nucleotide sequence of DNA (deoxyribonucleic acid). In nucleotide excision repair or NER, the damaged base along with a short stretch of healthy strand is removed and later the gap is refilled with correct nucleotides. Nucleotide definition is - any of several compounds that consist of a ribose or deoxyribose sugar joined to a purine or pyrimidine base and to a phosphate group and that are the basic structural units of nucleic acids (such as RNA and DNA). DNA has 1 phosphate, ATP has three phosphates . It automatically determines the format of the input. In DNA, the purine bases are adenine and guanine, while the pyrimidines are thymine and cytosine. Nucleotide definition, any of a group of molecules that, when linked together, form the building blocks of DNA or RNA: composed of a phosphate group, the bases adenine, cytosine, guanine, and thymine, and a pentose sugar, in RNA the thymine base being replaced by uracil. DNA (or deoxyribonucleic acid) is the molecule that carries the genetic information in all cellular forms of life and some viruses. DETERMINATION OF NUCLEOTIDE SEQUENCES IN DNA Nobel lecture, 8 December 1980 by FREDERICK SANGER Medical Research Council Laboratory of Molecular Biology, Cambridge, England INTRODUCTION In spite of the important role played by DNA sequences in living matter, it is only relatively recently that general methods for their determination have been developed. Because in DNA these sticks are nucleotide. 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