Common names include: awapuhi, bitter ginger, shampoo ginger (Malay = lempoyang) and pinecone ginger. Ginger History. Despite its tendency to spread, it has not been included on any invasive species lists and has been on the islands for over 1,000 years (i.e. It is also known to possess antioxidant and anti-inflammatory activities. As a result, the plant extracts were inactive against the enzyme activity of β-hexosaminidase. Zingiber zerumbet, ‘Awapuhi or Shampoo Ginger, is a perennial multipurpose herbaceous plant. In other words, it can be planted in places where most plants will not live. This ginger relative grows to heights of about two to four feet. Research on the mechanisms of zerumbone in inhibition of proliferation and induction of apoptosis in human esophageal cancer cell line Eca-109. Zingiber zerumbet: Taxonomy navigation › Zingiber. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials: A Review, Antiproliferative and antiangiogenic effects of zerumbone from Zingiber zerumbet L. Smith in sprague dawley rat model of hepatocellular carcinoma, Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide, INHIBITORY EFFECT OF ZERUMBONE ON MIGRATION OF COLORECTAL CANCER CELLS VIA DOWN-REGULATION OF MATRIX METALLOPROTEINASE-13 …, Molecular docking, MD simulation, DFT and ADME-toxicity study on analogs of zerumbone against IKK-β enzyme as anti-cancer agents, Prophylactic and Therapeutic Efficacies of Dietary Zerumbone Supplementation on the Pathogenesis of Atherosclerosis in Cholesterol-fed Rabbits, ANTI-LEUKEMIC EFFECTS OF ZERUMBONE NANOPARTICLE ON HUMAN LYMPHOBLASTIC LEUKEMIA CELLS (JURKAT) IN VITRO AND MURINE …, Lewis-Acid-Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC PROPERTIES OF ZERUMBONE AND THEIR MECHANISMS OF ACTION IN MICE MODEL OF NEUROPATHIC …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF ZERUMBONE THROUGH INVOLVEMENT OF MONOAMINERGIC PATHWAYS IN MICE MODEL …, COMPARISON STUDY OF THE EFFECTS OF ZERUMBONE AND AG490 IN HUMAN RENAL CELL CARCINOMA ON THE ACTIVATION OF THE JANUS KINASE …, CYTOTOXICITY AND MECHANISMS OF ACTION OF ZERUMBONE-LOADED NANOSTRUCTURED LIPID CARRIER IN TRIPLE NEGATIVE BREAST CANCER …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITIES OF ZERUMBONE IN CHRONIC CONSTRICTION INJURY-INDUCED NEUROPATHIC PAIN AND …, Potential chemoprevention of dimethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, … Obat Antikanker Payudara dari Lempuyang Gajah dan Lempuyang Emprit dengan Kontrol Kualitas Berbasis Senyawa Penanda Zerumbone dan Aktivitas Antikanker …, Zerumbone Protects against Carbon Tetrachloride (CCl4)-Induced Acute Liver Injury in Mice via Inhibiting Oxidative Stress and the Inflammatory Response: Involving …, … of ATF3 for ER Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to TRAIL-mediated Apoptosis Through Upregulation of DR5 by Zerumbone …, Study on transformation of zerumbone with fatty acid hydrazides, Hormetic Effects of Zerumbone in Proteostasis, Zerumbone 처리에 따른 Helicobacter pylori 의 단백질 비교분석, CYTOTOXICTY OF ZERUMBONE AGAINST LIVER CANCER CELL LINES (HepG2) VIA APOPTOSIS ACTIVITY, Comparative Proteome Analysis of Zerumbone-treated Helicobacter pylori, Nghiên cứu các phương pháp phân lập Zerumbone có chất lượng cao từ thân rễ cây gừng gió (zingiber zerumbert sm.) I’ve seen this plant for sale at local nurseries, too. These findings might suggest possible chemopreventive ability of zerumbone, through suppression of COX-2 expression, cell proliferating activity of colonic mucosa, and induction of phase II detoxification enzymes in the development of carcinogen-induced ACF. Your email address will not be published. This study showed promising avenues towards zerumbone to be developed as a new chemo-natural drug for treatment of cervical cancer. County Herbaria Literature Citation (If Applicable) Alachua: FLAS : Citrus: PIHG Hillsborough: USF Lake: PIHG Leon: FSU + Expand All - Collapse Synonyms – Denotes synonyms that are applicable to the state. Also see: Which Foods Have More Vitamin C . Plus de photos de Zingiber zerumbet Famille: zingiberaceae. Terminal (leaf) node. The authority listed in The Plant List (2013) is Zingiber zerumbet (L.) Roscoe ex Sm. “Zingiber” is originally from a Sanskrit word that means “shaped like a horn” and refers to the horn-shaped leaves of most species of ginger. 1805. Mandatory FDA Disclaimer Privacy Policy Terms and Conditions Have Questions? This receptor mediates homing of tumor cells to specific organs that express the ligand CXCL12 for this receptor. Zingiber Zerumbet-Smith brought all of it back, and after a lifetime of straight hair actually made it curly and lots thicker. For a few months, I was confused about that whole situation until I allowed some of the rhizomes he gave me to grow out. Introduction. so yes ,what is the price + sent cost; Part 5: Structural transformation of the dimethylamine derivatives, Zerumbone: a natural compound with anti-cholinesterase activity, Antibacterial and antimutagenic activities of novel zerumbone analogues, Zerumbone, an anti‐inflammatory phytochemical, induces expression of proinflammatory cytokine genes in human colon adenocarcinoma cell lines, Cytotoxicity against cholangiocarcinoma cell lines of zerumbone derivatives, Zingiberaceous and citrus constituents, 1′-acetoxychavicol acetate, zerumbone, auraptene, and nobiletin, suppress lipopolysaccharide-induced cyclooxygenase-2 …, Evaluation of the genotoxicity of zerumbone in cultured human peripheral blood lymphocytes, Zerumbone‐Induced Antinociception: Involvement of the l‐Arginine‐Nitric Oxide‐cGMP ‐PKC‐K+ATP Channel Pathways, The chemistry of zerumbone IV: asymmetric synthesis of Zerumbol. It is widely distributed in South East Asia. 2: 105 1806 . Plant List . Constituents of the essential oils of rhizomes of three Zingiberaceae: Zingiber zerumbet Smith, Hedychium coronarium Koenig and Etlingera cevuga Smith. The name Zingiber actually stems from a Sanskrit word which means a Bull's Horn. Pinecone ginger typically grows to about 7 feet tall, but varieties such as “Darceyi” (Zingiber zerumbet “Darceyi”) are smaller, reaching only about 4 feet. Zingiber blancoi Hassk. In the family Zingiberaceae, this fragrant ornamental perennial has leafy stems growing from a forked (sympodial) underground, fleshy rhizome-stem. : it’s generally not a problematic plant). The rhizome has traditionally been used in medicinal applications as an anti-inflammatory, anti-diarrheal, de-wormer, and for various types of pain management. This review summarizes the data based on various in vitro and in vivo studies related to the effects of zerumbone on numerous pivotal molecular targets in cancer and its reported chemopreventive/therapeutic effects in different models of cancer. The … Antimicrobial activity of the crude extract, fractions and isolation of zerumbone from the rhizomes of Zingiber roseum. is an accepted name This name is the accepted name of a species in the genus Zingiber (family Zingiberaceae ). As soon as the flower came out, I knew what had happened! Simplified isolation, conjugate addition reactions, and a unique ring contracting transannular reaction of its dibromide, Zerumbone inhibits interleukin-6 and induces apoptosis and cell cycle arrest in ovarian and cervical cancer cells, Zerumbone abolishes RANKL-induced NF-κB activation, inhibits osteoclastogenesis, and suppresses human breast cancer–induced bone loss in athymic nude mice, Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, Zerumbone, a Southeast Asian ginger sesquiterpene, induced apoptosis of pancreatic carcinoma cells through p53 signaling pathway, Zerumbone inhibits angiogenesis by blocking NF-κB activity in pancreatic cancer, Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human HeLa cervical cancer cells, The chemistry of zerumbone. Total synthesis of zerumbone, … cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and …, The chemistry of zerumbone. and ive stored it in the fridge over a month with it being fine. Zerumbone suppresses osteopontin-induced cell invasion through inhibiting the FAK/AKT/ROCK pathway in human non-small cell lung cancer A549 cells, Zerumbone, a phytochemical of subtropical ginger, protects against hyperglycemia-induced retinal damage in experimental diabetic rats, Zerumbone protects INS-1 rat pancreatic beta cells from high glucose-induced apoptosis through generation of reactive oxygen species, Anticancer activity of the bioreductive and non-bioreductive zerumbone derivatives, Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions, Development and validation of an HPTLC method for analysis of zerumbone, the anticancer marker from Zingiber zerumbet, Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway, Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between …, Promotion of p53 expression and reactive oxidative stress production is involved in zerumbone-induced cisplatin sensitization of non-small cell lung cancer cells, Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway, Inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin induces apoptosis in liver hepatocellular HepG2 cells via caspase 8/bid cleavage switch and …, Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone, Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells, A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes, Contribution to the Study of Essential Oil of Xylopia Aethiopica (DUNAL) A. The cytotoxicity of zerumbone and cisplatin were investigated using the MTT assay and caspases-3 was estimated with colorimetric assay in zerumbone treated HeLa cells. Shoots are spicy and consist of the still folded leaves as they emerge. Zingiber cochinchinense Gagnep. ‘Awaphui can form dense thickets, so allow them to have a lot of space, or plan to manage them annually. I accidently ate ‘awapuhi! It took me awhile before I found my first ‘awapuhi plant. Alpinia zerumbet, commonly known as shell ginger, is a perennial species of ginger native to East Asia.They can grow up to 8 to 10 ft (2.4 to 3.0 m) tall and bear colorful funnel-shaped flowers. Articles & Resources . The liquid from the inflorescence is drinkable. Regulation of ring bond cleavage and unique antibacterial activities of zerumbone derivatives, Preliminary analysis of the antinociceptive activity of zerumbone, Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis …, Antitumor effects of zerumbone from Zingiber zerumbet in P-388D1 cells in vitro and in vivo, Attractive reactivity of a natural product, zerumbone, Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation …, Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells, Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination, Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive …, Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas‐and mitochondria‐mediated pathway, Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer, Nuclear magnetic resonance spectroscopy. Two years later, I was able to dig up that original clump and spread it around to create many more plants, some of which I planted in a waterway where not many other plants want to grow. The shoots, rhizomes and inflorescence liquid are all consumable. Zingiber zerumbet Smith. Now I get it watch it thrive and utilize the many flowers it creates!! not really sure where they would be found in your location. Leaves 15-35 x 4-7.5 cm, oblong or oblong-lanceolate, base obtuse, apex acuminate, pubescent below; ligule to 2.5 cm long. This plant will thrive in heavy shade and waterlogged soils. Source. A Floridata plant profile of species Zingiber zerumbet, commonly called pinecone ginger, shampoo ginger, Awapuhi kuahiwi (Hawaii) Home . Pinecone ginger grows in USDA zones 8 through 11. Thus, agents that can down-regulate CXCR4 expression have potential against cancer metastasis. We suggest that the economic cultivation period of Z. zerumbet is the 5th month after seeding when its functions as food and anti-inflammatory are maximum, because 1 is dramatically increased at that time. 1. Milking may be done repeatedly if left on the plant. ‘Awapuhi does not produce seed and is only propagated by division. Zerumbone was also found to inhibit the proliferation of non-malignant Chang Liver and MDBK cell lines. Zingiber zerumbet is widely used as therapeutic agent in traditional medicine and is reported to exert antioxidant activities. Required fields are marked *. ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS, ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS, FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN, JNK ACTIVATION PREVENTS PREMATURE SENESCENCE, NRF2: MASTER REGULATOR OF THE AGING PROCESS, SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG), INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL, Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes, Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice, Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio, Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone, Studies in sesquiterpenes—XVI: Zerumbone, a monocyclic sesquiterpene ketone, Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice, Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice, Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet, Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells, In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa), Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect, Zerumbone, an HIV-inhibitory and cytotoxic sesquiterpene of Zingiber aromaticum and Z. zerumbet, Anticancer and antimicrobial activities of zerumbone from, Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin, Chemistry of zerumbone. Common name i: Shampoo ginger: Synonym i: Amomum zerumbet: Other names i ›Zingiber darceyi ›Zingiber darceyi H.J.Veitch ›Zingiber zerumbet (L.) Sm. Zerumbone: a potential fungitoxic agent isolated from Zingiber cassumunar Roxb. Zingiber zerumbet, ‘Awapuhi or Shampoo Ginger, is a perennial multipurpose herbaceous plant. not totally sure. The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). RICH: Isolation and Characterization of Zerumbone, Effects of selected physicochemical parameters on zerumbone production of Zingiber zerumbet Smith cell suspension culture, Zerumbone induces gastric cancer cells apoptosis: Involving cyclophilin A, Zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, attenuates nonalcoholic fatty liver disease in hamsters fed on high-fat diet, Genotoxicity assessment of a natural anticancer compound zerumbone in CHO cell lines, Novel synthesis of zerumbone-pendant derivatives and their biological activity, Zerumbone suppresses the activation of inflammatory mediators in LPS-stimulated U937 macrophages through MyD88-dependent NF-κB/MAPK/PI3K-Akt signaling …, Zerumbone, a sesquiterpene, controls proliferation and induces cell cycle arrest in human laryngeal carcinoma cell line Hep-2, Antiallodynic and antihyperalgesic effects of zerumbone on a mouse model of chronic constriction injury-induced neuropathic pain, Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model, Biotransformation of zerumbone by Caragana chamlagu, Zerumbone significantly improved immunoreactivity in the synovium compared to Channa striatus extract in monosodium iodoacetate (MIA)-induced knee …, Binding mode analysis of zerumbone to key signal proteins in the tumor necrosis factor pathway, Possible contribution of zerumbone-induced proteo-stress to its anti-inflammatory functions via the activation of heat shock factor 1, Zerumbone reduced the inflammatory response of acute lung injury in endotoxin-treated mice via Akt-NFκB pathway, Zerumbone, a Cyclic Sesquiterpene from Zingiber zerumbet Induces Apoptosis, Cell Cycle Arrest, and Antimigratory Effects in SW480 Colorectal Cancer Cells, Zerumbone induces mitochondria-mediated apoptosis via increased calcium, generation of reactive oxygen species and upregulation of soluble histone H2AX in …, Comparison of apoptotic inducing effect of zerumbone and zerumbone-loaded nanostructured lipid carrier on human mammary adenocarcinoma MDA-MB-231 cell …, Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts, Effect of Zingiber zerumbet Essential Oils and Zerumbone Inhalation on Body Weight of Sprague Dawley Rat* I. Batubara,“I H. Suparto,” S. Sadiah,“R. Singapore 48: 228. African Blue Basil (Ocimum kilimandscharicum x basilicum ‘Dark Opal’), Hawaiian Cocktail Pepper (Capsicum chinense), Hawaiian Hot Pepper (Capsicum frutescens), Litte Fire Ant (Wasmannia auropunctata) Prevention and Protocol, Observations/Recommendations for Lava Zone 1, Propagation: Soil Mixes, Potting and Fertilizing, Winged bean (Psophocarpus tetragonolobus). Research carried out using different in vitro and in … 2: 105, t. 112. Zerumbone significantly showed an antiproliferative activity upon HepG2 cells with an IC50 of 3.45 ± 0.026 μg/ml. is an important monocotyledonous plant belonging to Zingiberaceae commonly known as shampoo ginger or pinecone ginger. Love this Website? Dicot Families . Contact David Rodriguez to build you one! Zingiber amaricans Blume. In this study, we report the identification of zerumbone, a component of subtropical ginger (Zingiber zerumbet), as a regulator of CXCR4 expression. Have you ever heard of anyone storing the mucilage long term? 1806, although many consider 1805 the year when this work was published. Zingiber zerumbet (L.) Roscoe ex Sm., Zingiberaceae, is a perennial, aromatic and tuberose plant that grows in humid locations. They are grown as ornamentals and their leaves are used in cuisine and traditional medicine. Or a address where I can buy; A lectotypification made by Theilade (Gard. Zingiber zerumbet is a species of plant in the ginger family with leafy stems growing to about 1.2 m (3.9 ft) tall. A few months later, another friend gave me a bunch of his harvested “edible ginger” (Zingiber officinale). I deduced that any herb that could have such an effect on hair, as well as fingernails (mine got much stronger on the powder) must have other wonderful effects on the body. It can be concluded that, potent antibacterial and antifungal phytochemicals are present in ethanol extract of Z. zerumbet (L). Synonymes: * Zingiber aromaticum Valeton (1918) * Amomum zerumbet L. Ethymologie: Le terme Shampoo provient du liquide clair, visqueux-savonneux, à odeur de gingembre contenu dans les inflorescences. Bull. Zingiber ovoideum Blume. Bot. Type: INDIA: ** Not applicable or data not available. Ask a friend growing the plant for some rhizomes! Abstract. This new anticancer bioactive compound from Z. zerumbet was investigated for its activity and mechanism in … Zingiber littorale (Valeton) Valeton. According to the in vitro study, 1 had greater anti-inflammatory effects than 2. Zingiber zerumbet Amome sauvage . Matthes HWD, Luu B, Ourison G (1980) … The type for Z. zerumbet is still to be sought among several syntypes. Pinecone ginger (Zingiber zerumbet), which is also sometimes called shampoo ginger, produces showy, pinecone-shaped flower bracts. 2011). All flowering plants are called angiosperms. In the next study they assessed the effects of zerumbone on cell proliferation activity of crypts by counting silver-stained nucleolar organizer regions protein (AgNORs) in colonic cryptal cell nuclei. Masuda T, Jitoe A, Kato S, Nakatani N (1991) Acetylated flavonol glycosides from Zingiber zerumbet. Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2, Immunomodulatory effects of zerumbone isolated from roots of Zingiber zerumbet, Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis, Zerumbone suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells, Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials, Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced …, Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis, Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone, Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice, Antisecretory, gastroprotective, antioxidant and anti-helicobcter pylori activity of zerumbone from Zingiber Zerumbet (L.) Smith, Dietary zerumbone prevents against ultraviolet B-induced cataractogenesis in the mouse, Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA …, Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia …, Zerumbone isolated from Zingiber zerumbet inhibits inflammation and pain in rats, Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells, Molecular cloning and functional characterization of α-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet …, Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology, Crystal structure of zerumbone [(E, E, E)-2, 6, 9, 9-Tetramethylcycloundeca-2, 6, 10-trien-1-one], Unprecedented olefin-dependent histidine–kinase inhibitory of zerumbone ring-opening material, Zerumbone causes Bax-and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo, Optimization of SC–CO2 extraction of zerumbone from Zingiber zerumbet (L) Smith, Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: involvement of mitochondria-regulated …, Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-induced hepatic injury, Zerumbone exerts antiproliferative activity via apoptosis on HepG2 cells, Transannular cyclizations of zerumbone epoxide, High content of zerumbone in volatile oils of Zingiber zerumbet from southern India and Malaysia, Zerumbone, an electrophilic sesquiterpene, induces cellular proteo-stress leading to activation of ubiquitin–proteasome system and autophagy, Hepatoprotective action of zerumbone against paracetamol induced hepatotoxicity, Zerumbone inhibits growth of hormone refractory prostate cancer cells by inhibiting JAK2/STAT3 pathway and increases paclitaxel sensitivity, Chondroprotective effect of zerumbone on monosodium iodoacetate induced osteoarthritis in rats, Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells, Exploring the immunomodulatory and anticancer properties of zerumbone, Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model, Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance, In vivo and In vitro Genotoxic Effects of Zerumbone, Comparative study on inhibitory activity of zerumbone and zerumbone 2, 3-epoxide on NF-κB activation and NO production, Combination of zerumbone and cisplatin to treat cervical intraepithelial neoplasia in female BALB/c mice, Remarkable synthesis and structure of allene type zerumbone, Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics, Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model, Synthesis of a novel inhibitor against MRSA and VRE: preparation from zerumbone ring opening material showing histidine-kinase inhibition, Synthesis of macrocyclic terpenoids by intramolecular cyclization. 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Media in category `` Zingiber zerumbet, commonly called pinecone ginger, hopefully adding to insights. Of Zingiber roseum friend growing the plant for some rhizomes words, can! Seed and is only propagated by division zones 8 through 11 the still folded leaves as emerge... To heights of about two to four feet, Zingiber spectabile, comes from words. ):55–59 Google Scholar with it being fine anti-inflammation, chemoprevention, and for various types pain... Ligule to 2.5 cm long details about the particular brand you use.The FDA has not reviewed product... The essential oils of rhizomes of three Zingiberaceae: Zingiber zerumbet Smith phytochemical has! And Etlingera cevuga Smith when I first started my garden, I was interested... So allow them to have a lot of space, or plan to manage them annually used... Proliferation of non-malignant Chang Liver and MDBK cell lines in cuisine and traditional medicine the genus Zingiber ( family )!